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Related Experiment Videos

ICD nocardiosis.

Sean O'Rourke1, Shalini Kapoor, Danielle Carter-Adkins

  • 1Health Sciences Center, State University of New York at Stony Brook, Stony Brook, New York, 11794-8171, USA.

Journal of Interventional Cardiology
|November 8, 2003
PubMed
Summary

Nocardia asteroides can infect implantable cardioverter defibrillators. Complete lead system removal is crucial to prevent persistent infection and chronic pleuropericardial disease.

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Area of Science:

  • Cardiology
  • Infectious Diseases
  • Medical Device Infections

Background:

  • Implantable cardioverter defibrillators (ICDs) are vital for managing cardiac arrhythmias.
  • Device-related infections pose a significant challenge in cardiovascular implantable electronic devices.
  • Nocardia asteroides is an opportunistic pathogen rarely associated with ICD infections.

Observation:

  • A case of Nocardia asteroides infection involving an ICD is reported.
  • The infection persisted systemically despite pulse generator removal and prolonged antibiotic treatment.
  • Chronic pleuropericardial disease developed in the absence of epicardial lead system removal.

Findings:

  • Nocardia asteroides ICD infection can be refractory to standard treatment protocols.
  • Pulse generator explant alone may be insufficient to eradicate the infection.
  • Epicardial lead system retention is associated with the development of chronic sequelae.

Implications:

  • Highlights the potential for Nocardia asteroides to cause severe ICD infections.
  • Underscores the importance of considering lead system removal in refractory cases.
  • Suggests that complete device removal, including leads, may be necessary for successful treatment and prevention of complications.

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