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Human metapneumovirus infection in Thai children
Wanida Thanasugarn1, Rujipat Samransamruajkit, Pijitra Vanapongtipagorn
1Viral Hepatitis Research Unit, Department of Paediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Scandinavian Journal of Infectious Diseases
|November 11, 2003
Abstract:
Human metapneumovirus (hMPV) associated with clinical respiratory tract infection (RTI) in children was first isolated in The Netherlands. Of 120 Thai paediatric patients with RTI examined, 5 cases (4.2%) showed detectable hMPV based on N-gene-specific RT-PCR. All of them were negative for hRSV infection. Aligning the sequences with a reference strain revealed some nucleotide differences, which necessitates future investigation to evaluate clinical significance and genotype variation.