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Necrotizing eosinophilic folliculitis with mucinosis
1Skin and Cancer Foundation Australia, Sydney, New South Wales, Australia. skossard@scfa.edu.au
The Australasian Journal of Dermatology
|November 18, 2003
Summary
A woman presented with a facial eruption of crusted plaques and eschar. Histology revealed eosinophilic folliculitis and mucinosis, suggesting Ofuji's disease, which rapidly improved with indomethacin.
Area of Science:
- Dermatology
- Histopathology
Background:
- Ofuji's disease is a rare inflammatory skin condition.
- Eosinophilic folliculitis can present with varied clinical and histological features.
Observation:
- A 23-year-old woman developed a 2-week history of an extensive facial eruption.
- The eruption consisted of crusted, arciform plaques with hemorrhagic eschar, originating from pruritic follicular pustules.
- Facial edema was present, but no systemic symptoms or fever were reported.
Findings:
- Skin biopsies showed prominent tissue eosinophilia, eosinophilic folliculitis, and follicular mucinosis.
- Hemorrhagic scale crust was observed on the surface.
- The findings suggested a necrotizing variant of eosinophilic folliculitis or a florid form of Ofuji's disease.
Implications:
- The case highlights a potential necrotizing variant of eosinophilic folliculitis.
- It presents a florid manifestation of Ofuji's disease in a non-atopic individual.
- Rapid response to indomethacin suggests its efficacy in treating this presentation.