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Cytotoxic activity of Ozoroa insignis from Zimbabwe
Angela I Rea1, Jennifer M Schmidt, William N Setzer
1Department of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA.
Fitoterapia
|November 25, 2003
Abstract:
The crude methanol bark extract of the Zimbabwean medicinal plant, Ozoroa insignis, showed in-vitro cytotoxic activity against Hep-G2 (human hepatocellular carcinoma), MDA-MB-231 (human mammary adenocarcinoma), and 5637 (human primary bladder carcinoma). Bioactivity-directed chromatographic separation led to isolation of anacardic acid and ginkgoic acid as the cytotoxic components.
