Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mammalian development in space.

April E Ronca1

  • 1Life Sciences Division, NASA Ames Research Center, Moffett Field, CA 94035, USA. aronca@mail.arc.nasa.gov

Advances in Space Biology and Medicine
|November 25, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Female reproductive dysfunction and transgenerational consequences following prolonged spaceflight exposure.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Impact of near continuous low dose rate neutron irradiation on pregnancy outcomes in mice.

NPJ microgravity·2024
Same author

A second space age spanning omics, platforms and medicine across orbits.

Nature·2024
Same author

Sexual dimorphism during integrative endocrine and immune responses to ionizing radiation in mice.

Scientific reports·2024
Same author

Galactic Cosmic Irradiation Alters Acute and Delayed Species-Typical Behavior in Male and Female Mice.

Life (Basel, Switzerland)·2023
Same author

Neuro-consequences of the spaceflight environment.

Neuroscience and biobehavioral reviews·2021
Same journal

Primates in space flight.

Advances in space biology and medicine·2005
Same journal

Gravity effects on life processes in aquatic animals.

Advances in space biology and medicine·2005
Same journal

Responses across the gravity continuum: hypergravity to microgravity.

Advances in space biology and medicine·2005
Same journal

Use of animal models to study skeletal effects of space flight.

Advances in space biology and medicine·2005
Same journal

Development as adaptation: a paradigm for gravitational and space biology.

Advances in space biology and medicine·2005
Same journal

Effect of space flight on circadian rhythms.

Advances in space biology and medicine·2005
See all related articles

Mammalian reproduction and development in space are significantly impacted by the absence of gravity. Weightlessness alters maternal-offspring interactions, complicating research on fetal and early postnatal development in space. Further studies are needed.

Area of Science:

  • Space biology
  • Developmental biology
  • Mammalian reproduction

Background:

  • Mammalian life evolved under Earth's gravity, raising questions about reproduction and development in space.
  • Spaceflight impacts critical reproductive and developmental phases, including fertilization, embryogenesis, pregnancy, birth, and postnatal maturation.

Purpose of the Study:

  • To review the current knowledge of spaceflight effects on mammalian reproduction and development.
  • To emphasize fetal and early postnatal life, where most mammalian spaceflight data exists.
  • To highlight the importance of the maternal-offspring system in interpreting spaceflight effects.

Main Methods:

  • Review of existing mammalian spaceflight data, focusing on fetal and early postnatal development.
  • Analysis of studies on rats at different developmental stages (mid-pregnant, early postnatal).

Related Experiment Videos

  • Consideration of challenges in in-flight caging and maternal-offspring interactions.

    • Main Results:

    • Spaceflight alters maternal-offspring interactions, affecting the interpretation of developmental effects.
    • Studies of mid-pregnant rats in space have been successful.
    • Studies of early postnatal rodents have faced challenges due to caging and compromised maternal care.

    Conclusions:

    • Biologically meaningful maternal-offspring interactions are changed in weightlessness.
    • There is a strong need for new studies on mammalian reproduction and development in space.
    • Habitat development and ground-based testing are crucial for future research, especially with young rodents.