Prospective identification of the risk of SIDS

In the general population, there are a number of epidemiologic and physiologic factors that have been identified as increasing the risk for SIDS. To date, optimum combinations of these factors do not sufficiently discriminate the high-risk infant in order to serve as a basis for prospective screening. In the subsequently born sibling, the risk is only slightly increased, and, again, there are no factors that discriminate the infant at risk of death. Among infants who have sustained an ALTE, there are several identifiable causes or physiologic factors associated with high risk for a repeated event. This article has reviewed the association between risk factors and death in each of these three categories of patients.