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Epitope mapping of pneumococcal surface protein A of strain Rx1 using monoclonal antibodies and molecular structure

Jan Kolberg1, Audun Aase, Gunnhild Rødal

  • 1Department of Airborne Infections, Norwegian Institute of Public Health, P.O. Box 4404, Nydalen, 0403 Oslo, Norway. jan.kolberg@fhi.no

FEMS Immunology and Medical Microbiology
|December 4, 2003
PubMed

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Antibody Structure01:10

Antibody Structure

Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...