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Updated: Aug 29, 2026
Transplantation of Olfactory Ensheathing Cells to Evaluate Functional Recovery after Peripheral Nerve Injury
Published on: February 23, 2014
[An study on functioning remobilization of the paralyzed vocal cord by latero-terminal neurorrhaphy in rats]
Hongjian Liu1, Mingmin Dong, Weihua Lou
1Department of Otorhinolaryngology, First Clinic Medical College of Zhengzhou University, Zhengzhou 450052.
Objective:
To investigate the effect and the clinic value of latero-terminal neurorrhaphy to treat vocal cord paralysis.
Method:
Sixty SD rats were divided into three groups. In the experimental group, the right recurrent laryngeal nerve(RLN) was incised and anastomosed to the right phren nerve by means of latero-terminal neurorrhaphy. The internal nerve of the right RLN was incised and anastomosed to the right ansa cervicals nerve by end-to-end nerve anastomosis. In control group, the right RLN was incised and sutured to the right phren nerve by end-to-end nerve anastomosis. The internal nerve of the right RLN were incised and anastomosed to the right ansa cervicals nerve by end-to-end nerve anastomosis. In normal group rats, the nerves were only exposed. One to three months later, 10 rats from each group were examined for vocal cord movement and nerve regeneration by using fibrolaryngscope and nerve electromyography.
Result:
One months after operation. This effect of latero-terminal neurorrhaphy had significant difference compared with the control group (P < 0.05). Three months after operation. This effect of latero-terminal neurorrhaphy had not significant difference compared with the control group (P > 0.05).
Conclusion:
The latero-terminal neurorrhaphy has a similar treatment effect compared with end-to-end nerve anastomosis. This microsurgical technique provides a new method for treating vocal cord paralysis.
