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[The pro-dependent folding of microbial proteolytic enzymes]
I V Demidiuk1, M V Zabolotskaia, N S Velishaeva
1Institute for Molecular Genetics, Russian Academy of Medical Sciences, Moscow.
Molekuliarnaia Genetika, Mikrobiologiia I Virusologiia
|December 11, 2003
Abstract:
Modern published data on the folding of microbial proteolytic enzymes mediated through their pro-parts, or on a so-called pro-dependent folding, are surveyed. Various aspects related with the functioning of pro-sequences are under discussion. The possibility to build up, on the basis of one and the same amino-acid sequence, the special protein conformers involving different pro-peptides is in the focus of attention.