Related Experiment Video
Updated: Aug 29, 2026

Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure
Published on: December 2, 2014
Postinfarction remodeling of the heart: types of pathomorphological changes in the right ventricle
V D Rozenberg1, L M Nepomnyashchikh
1Department of General Pathology and Pathomorphology, Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk.
Abstract:
New geometric characteristics of the right ventricle depended on the localization of macrofocal transmural scars in the left ventricle of postinfarction heart. Most pronounced changes in the right ventricle were observed during dilatational and hypertrophic remodeling of the heart. The increase and decrease in the volume were most frequently occurring and pathognomonic forms of pathomorphological changes in the right ventricle. Dilatational remodeling was accompanied by a decrease in the volume of the right ventricle. The increase in the volume of this ventricle was typical of hypertrophic remodeling. Pathological variability in the right ventricle underlies the development of severe disturbances in intracardiac hemodynamics, i.e., patho- and thanatogenesis of postinfarction heart.
Related Concept Videos
Heart Failure II: Pathophysiology
Mitral Regurgitation I: Introduction
Pathophysiology of Heart Failure
Cardiomyopathy I: Introduction and Classification
Myocarditis I: Introduction
Mitral Stenosis I: Introduction
