Outcomes in esophageal atresia and tracheoesophageal fistula
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Updated: Aug 29, 2026

An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function
Published on: April 17, 2020
David E Konkin1, Wael A O'hali, Eric M Webber
1Department of Surgery, British Columbia's Children's Hospital, University of British Columbia, Vancouver, BC, Canada.
Insights
The Spitz classification best predicts survival for newborns with esophageal atresia (EA) and tracheoesophageal fistula (TEF). Management of gastroesophageal reflux has shifted from surgery to medication.
Area of Science:
- Pediatric Surgery
- Neonatology
- Congenital Anomalies
Background:
- Esophageal atresia (EA) and tracheoesophageal fistula (TEF) are congenital anomalies requiring surgical intervention.
- Accurate prognostic classification is crucial for predicting outcomes in affected newborns.
- Associated anomalies and complications significantly impact patient management and survival rates.
Purpose of the Study:
- To evaluate the effectiveness of different prognostic classifications for esophageal atresia (EA) and tracheoesophageal fistula (TEF).
- To analyze the incidence and types of complications following surgical repair of EA/TEF.
- To assess trends in managing gastroesophageal reflux in infants with EA/TEF.
Main Methods:
- Retrospective chart review of 144 infants treated for EA/TEF at British Columbia Children's Hospital (1984-2000).
- Analysis of patient demographics, associated anomalies, management strategies, and outcomes.
- Comparison of survival rates across Waterston, Montreal, Spitz, and Bremen prognostic classifications.
Main Results:
- The Spitz classification demonstrated the strongest correlation with survival rates (Type I: 99%, Type II: 84%, Type III: 43%; P < .05).
- Common complications included stricture (52%), gastroesophageal reflux (31%), and anastomotic leakage (8%).
- Management of gastroesophageal reflux shifted from fundoplication to medical management post-1992.
Conclusions:
- The Spitz classification is the most applicable prognostic tool for EA/TEF patients.
- Current management trends favor medical over surgical treatment for gastroesophageal reflux after EA/TEF repair.
- Understanding prognostic factors and complication patterns is vital for optimizing care in EA/TEF infants.
Background/Purpose:
The purpose of this analysis was to investigate outcomes in newborns with esophageal atresia (EA) or tracheoesophageal fistula (TEF) with respect to prognostic classifications and complications.
Methods:
Charts of all 144 infants with EA/TEF treated at British Columbia Children's Hospital (BCCH) from 1984 to 2000 were reviewed. Patient demographics, frequency of associated anomalies, and details of management and outcomes were examined.
Results:
Applying the Waterston prognostic classification to our patient population, survival rate was 100% for class A, 100% for class B, and 80% for class C. The Montreal classification survival rate was 92% for class I and 71% for class II (P =.08). Using the Spitz classification, survival rate was 99% for type I, 84% for type II, and 43% for type III (P <.05). The Bremen classification survival rate was 95% "without complications" and 71% "with complications." Complications included stricture (52%), gastroesophageal reflux (31%), anastomotic leakage (8%), recurrent fistula (8%), and pneumonia (6%). Seventeen patients underwent fundoplication for gastroesophageal reflux, 16 pre-1992 and one post-1992.
Conclusions:
Comparing the major prognostic classifications, the Spitz classification scheme was found to be most applicable. In our institution, the trend in management of gastroesophageal reflux after repair of EA/TEF has moved away from fundoplication toward medical management.
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