Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Behçet syndrome.

Sebahattin Yurdakul1, Vedat Hamuryudan, Hasan Yazici

  • 1Division of rheumatology, Department of Medicin, Cerrahpasa Medical Faculty, University of Istanbul, Turkey.

Current Opinion in Rheumatology
|December 16, 2003
PubMed
Summary

Behçet syndrome (BS) research is advancing, with new insights into its pathogenesis and improved management options. Current findings confirm known associations and explore potential new targets for understanding this rare but increasingly studied condition.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Potential Confounding by Weight Loss: Comment on the article by Jorge et al.

Arthritis & rheumatology (Hoboken, N.J.)·2026
Same author

A critical look at disease classification/diagnosis criteria in rheumatology.

Current opinion in immunology·2026
Same author

EULAR recommendations for the management of Behçet's syndrome: 2025 update.

Annals of the rheumatic diseases·2026
Same author

A critical look at the evolution of randomized controlled trials: new and old ethical issues.

Current opinion in immunology·2026
Same author

Response to Commentary on "Factors associated with thrombosis in Behçet Syndrome: A systematic review and meta-analysis".

Seminars in arthritis and rheumatism·2025
Same author

Behçet's syndrome: one year in review 2025.

Clinical and experimental rheumatology·2025

Area of Science:

  • Immunology
  • Genetics
  • Rheumatology

Background:

  • Behçet syndrome (BS) is a rare multisystemic inflammatory disorder with increasing global research interest.
  • Understanding the pathogenesis of BS remains a significant challenge.

Purpose of the Study:

  • To review recent advancements in understanding Behçet syndrome (BS).
  • To highlight progress in the diagnosis and management of BS.

Main Methods:

  • Review of recent scientific publications and meeting abstracts on Behçet syndrome.
  • Analysis of genetic associations, immunological markers, and clinical observations.

Main Results:

  • Confirmed: males have more severe disease, thrombophilia in one-third of patients, association between papulopustular lesions and arthritis, increased gammadelta T cells, and HLA B51 as the primary genetic factor.
  • Identified potential pathogenetic insights: antibodies to Saccharomyces cerevisiae and alpha-enolase as a target antigen for antiendothelial cell antibodies.
  • Preliminary positive outcomes reported for anti-tumor necrosis factor agents in BS management.

Conclusions:

  • Significant progress has been made in understanding Behçet syndrome over the past two decades.
  • Current research offers more knowledge and therapeutic options for managing BS compared to previous years.

Related Experiment Videos