[Prognosis and prevention of infection in emergency surgery]

The results of treatment of 176 patients with sepsis at the department of urgent surgery in 1985-1990 are discussed. The authors suggest a stage complex program of acute surgical sepsis prevention, which consists of purposeful measures applied in the pre-, intra-, and postoperative period and includes the following recommendations: conduction of skin tests, preoperative injection of antibiotics, preoperative immunization of patients, immunological methods for the choice of antibiotics, methods for rational immunologic correction, phagotherapy. Besides, the authors developed and introduced into practice an individual method for prognosticating the course and outcome of acute surgical sepsis based on E. V. Gubler's (1978) mathematical method. It is concluded that the suggested methods are very effective, with their application the sepsis mortality rate reduced from 75% to 37.5%, i.e. by half.