Related Experiment Video
Updated: Aug 29, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
Published on: February 15, 2022
[Endothelial dysfunction in patients with open-angle glaucoma and atheromatous lesions]
Adriana Bulboacă1, A Bulboacă, Cristina Nicula
1Universitatea de Medicină şi Farmacie, Cluj-Napoca.
Unlabelled:
A number of observations revealed that the haemodynamic alteration may contribute to pathogenesis of glaucomatous neuropathy. Endothelial dysfunction associated with atherosclerosis impaired the endothelial dependent vasodilatation.
Purpose:
To evaluate the relationship between the endothelial dysfunction (assessed by plasma NO level) and carotid stenosis degree în primary open angle-glaucoma patients.
Methods:
Carotid ultrasonography and plasma NOx level (nitrite and nitrate) were obtained from 3 groups of patients: group 1-patients with primary open angle-glaucoma and carotid stenosis; group 2-patients with carotid stenosis and group 3-healthy subjects.
Results:
A significant lower NO level (compared with group 3) and a significant higher carotid stenosis (compared with group 2) were found în primary open angle-glaucoma patients. There was a significant correlation between the NOx level and carotid stenosis.
Conclusions:
Assessing the carotid atherosclerotic plaques may be benefical for the patients with primary open angle-glaucoma. Pharmacological neuroprotection with NO precursors may be useful for the patients with carotid stenosis associated with primary open angle-glaucoma.
Related Concept Videos
Glaucoma: Overview
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Diabetic Retinopathy
Angle Closure Glaucoma: Treatment
Peripheral Artery Disease I: Introduction