Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diastolic dysfunction.

Sara Paul1

  • 1Hickory Cardiology Associates, 1771 Tate Blvd. SE, Suite 201, Hickory, NC 28602, USA. smcpaul@earthlink.net

Critical Care Nursing Clinics of North America
|January 14, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Real-World Effectiveness and Tolerability of Low Dose Naltrexone to Treat Chronic Pain: A Retrospective Cohort Study of One Pain Physician's Practice.

Journal of pain research·2025
Same author

Multiregional Implementation Initiative's Impact on Guideline-Based Performance Measures for Patients Hospitalized With Heart Failure: IMPLEMENT-HF.

Circulation. Heart failure·2025
Same author

Home-Time, Mortality, and Readmissions Among Patients Hospitalized With Heart Failure: A Baseline Prior to IMPLEMENT-HF.

Circulation. Heart failure·2024
Same author

Implantable Hemodynamic Monitors Improve Survival in Patients With Heart Failure and Reduced Ejection Fraction.

Journal of the American College of Cardiology·2024
Same author

Hemodynamically-Guided Management of Heart Failure Across the Ejection Fraction Spectrum: The GUIDE-HF Trial.

JACC. Heart failure·2022
Same author

The GUIDE-HF trial of pulmonary artery pressure monitoring in heart failure: impact of the COVID-19 pandemic.

European heart journal·2022
Same journal

A New Era of Nursing Innovation.

Critical care nursing clinics of North America·2026
Same journal

Advancing Outcomes Through Innovation.

Critical care nursing clinics of North America·2026
Same journal

The Arc of Nurse Anesthesia: From Battlefield Origins to Future Innovation.

Critical care nursing clinics of North America·2026
Same journal

A Sepsis-Informed Model of Accelerated Aging.

Critical care nursing clinics of North America·2026
Same journal

TeleCritical Care Reimagined: Efficiency Through Digital Communication Application.

Critical care nursing clinics of North America·2026
Same journal

Impacts and Outcomes of Intensive Care Unit Design.

Critical care nursing clinics of North America·2026
See all related articles

Diastolic heart failure has a lower mortality rate than systolic heart failure but remains higher than in healthy individuals. Further research is needed to improve diastolic heart failure treatment strategies.

Area of Science:

  • Cardiology
  • Heart Failure Research

Background:

  • Diastolic heart failure, while having better survival rates than systolic heart failure, still presents a significant mortality risk compared to age-matched controls.
  • Five-year mortality rates are approximately 50% for systolic heart failure and 25% for diastolic heart failure.
  • Outcomes in elderly patients (over 65) with systolic and diastolic dysfunction may show greater similarity.

Purpose of the Study:

  • To highlight the current understanding of diastolic heart failure management.
  • To emphasize the need for evidence-based treatment strategies.
  • To underscore the importance of ongoing research in diastolic heart failure.

Main Methods:

  • Review of existing literature and clinical guidelines for heart failure management.

Related Experiment Videos

  • Analysis of mortality data for systolic and diastolic heart failure.
  • Examination of current therapeutic approaches based on expert consensus and mechanistic understanding.

    • Main Results:

    • Diastolic heart failure demonstrates a higher mortality rate than age-matched controls, despite being lower than systolic heart failure.
    • Large-scale clinical trials evaluating specific therapies for diastolic heart failure are lacking.
    • Current management guidelines for diastolic heart failure are largely based on expert opinion and limited evidence.

    Conclusions:

    • While diastolic heart failure has a better prognosis than systolic heart failure, its mortality remains elevated.
    • There is a critical need for robust, evidence-based clinical trials to guide the management of diastolic heart failure.
    • Future research endeavors are essential to deepen the understanding and enhance treatment strategies for diastolic heart failure.