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Efficient synthesis of polysubstituted acylguanidines and guanylureas
Alan R Katritzky1, Boris V Rogovoy, Xiaohong Cai
1Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, Florida 32611-7200, USA. katritzky@chem.ufl.edu
The Journal of Organic Chemistry
|January 17, 2004
Abstract:
(Benzotriazol-1-yl)carboximidamides were applied for the preparation of polysubstituted acylguanidines and guanylureas. The reaction sequence utilized mild conditions and gave high yields for final compounds and intermediates. The protocol developed allows for variation of the substituents at all positions of the products.