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The effect of ejaculation on albumin excretion rate
I B Hirsch1, R Farkas-Hirsch, J S Herbst
1Department of Medicine, Mount Sinai Medical Center, Miami Beach, Florida.
Journal of Diabetes and Its Complications
|July 1, 1992
Summary
Ejaculation does not significantly impact albumin excretion rates in urine for non-diabetic men. This finding suggests that sexual activity does not need to be restricted before urine collection for albuminuria testing.
Area of Science:
- Nephrology
- Urology
- Endocrinology
Background:
- Microalbuminuria is a key predictor of diabetic nephropathy.
- Variations in daily albumin excretion rates are common.
- Seminal fluid contains protein and albumin, potentially affecting urine albumin measurements.
Purpose of the Study:
- To investigate the effect of ejaculation on albumin excretion rate (AER).
- To determine if patients should abstain from sexual activity before urine collection for AER testing.
Main Methods:
- Ten healthy, non-diabetic men provided 24-hour urine samples.
- Urine was collected after 3 days of abstinence, during a 24-hour period with ejaculation, and the day after ejaculation.
- Albumin excretion rate and urinary creatinine were measured.
Main Results:
- Mean AER (micrograms/min) was 4.8 +/- 0.7 (abstinence), 6.3 +/- 1.1 (sex day), and 4.9 +/- 1.0 (post-sex day).
- No significant differences in AER were observed between the three collection periods.
- Urinary creatinine excretion and clearance remained unchanged.
Conclusions:
- Ejaculation does not influence albumin excretion rate in non-diabetic individuals.
- Routine advice to refrain from sexual activity before urine collection for AER assessment is not necessary for this population.