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Related Experiment Videos

Neural crest cell migration in the developing embryo.

M Bronner-Fraser1

  • 1Developmental Biology Center, University of California, Irvine, CA 92717, USA.

Trends in Cell Biology
|November 1, 1993
PubMed
Summary
This summary is machine-generated.

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Neural crest cell migration is segmented in vertebrate embryos. This review explores factors controlling this process, including somitic mesoderm and neural tube influences.

Area of Science:

  • Developmental biology
  • Cell biology
  • Embryology

Background:

  • Vertebrate embryos feature neural crest cells that migrate to specific locations for differentiation into various cell types.
  • Neural crest cells originate uniformly from the neural tube but exhibit segmented migration patterns along the body axis.

Purpose of the Study:

  • To review recent advancements in understanding the mechanisms governing neural crest cell migration.
  • To explore the factors controlling the segmented migratory patterns of neural crest cells.

Main Methods:

  • Review of experimental embryology findings.
  • Synthesis of cell biology research.

Main Results:

  • Segmental migration in trunk levels is influenced by the somitic mesoderm.

Related Experiment Videos

  • Head region migration involves intrinsic neural tube information and extrinsic ectodermal influences.
  • Cell-cell and cell-extracellular matrix interactions play a role in neural crest cell migration initiation and movement.

    • Conclusions:

    • Recent research has shed light on the complex mechanisms controlling neural crest cell migration.
    • Both intrinsic and extrinsic factors, along with cell interactions, dictate the precise migratory pathways of neural crest cells.