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Ureteral mast cell tumor in a dog
Michele Steffey1, Kenneth M Rassnick, Brian Porter
1Departments of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA.
Journal of the American Animal Hospital Association
|January 23, 2004
Summary
A rare urinary tract mast cell tumor (MCT) was diagnosed in a dog with ureteral obstruction. This case highlights the uncommon presentation of extracutaneous MCTs in veterinary medicine.
Area of Science:
- Veterinary Oncology
- Comparative Pathology
Background:
- Mast cell tumors (MCTs) are common in dogs, typically arising in the skin.
- Extracutaneous MCTs are infrequently reported, and their behavior can vary significantly.
- Urinary tract involvement by MCTs is exceptionally rare in canine literature.
Observation:
- A 6-year-old mixed-breed dog presented with partial unilateral ureteral obstruction.
- A ureteral mass was surgically removed and diagnosed as a poorly differentiated mast cell tumor (MCT).
- The dog was euthanized 5 months later due to central nervous system signs, with necropsy revealing a choroid plexus tumor.
Findings:
- Histopathology confirmed the ureteral mass as a mast cell tumor (MCT).
- No recurrence or metastasis of the ureteral MCT was detected at necropsy.
- A concurrent, unrelated choroid plexus tumor was identified as the cause for euthanasia.
Implications:
- This case represents the first reported instance of a primary mast cell tumor (MCT) originating in the canine urinary tract.
- It expands the known spectrum of extracutaneous MCT presentations in dogs.
- Highlights the importance of thorough histopathological evaluation for unusual tumor locations.