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Peritoneal dissemination from central neurocytoma: case report
Maurício Coelho Neto1, Ricardo Ramina, Murilo Sousa de Meneses
1Neurosurgical Department, Instituto de Neurologia de Curitiba, Curitiba, PR, Brazil. mcoelho29@yahoo.com
Arquivos De Neuro-Psiquiatria
|February 6, 2004
Summary
Central neurocytoma, a rare glial tumor, can exhibit aggressive behavior and spread outside the central nervous system. This case highlights extraneural dissemination, emphasizing the need for careful monitoring and tailored treatment strategies.
Area of Science:
- Neuro-oncology
- Histopathology
Background:
- Central neurocytoma is a rare, low-grade neuroglial tumor.
- Its biological behavior is not fully understood, with some cases showing aggressive tendencies.
Observation:
- A pediatric case of recurrent central neurocytoma with peritoneal dissemination is presented.
- Tumor cells were identified in ascitic fluid, indicating spread to the peritoneum.
- The patient experienced rapid ascites formation, metabolic imbalance, and respiratory failure.
Findings:
- Central neurocytomas, despite being low-grade, can exhibit aggressive behavior and extraneural dissemination.
- Proliferative index evaluation may guide adjuvant therapy decisions.
- Ventriculoperitoneal shunts may be associated with extraneural dissemination.
Implications:
- This case underscores the potential for aggressive behavior and extraneural spread in central neurocytoma.
- Careful patient selection for adjuvant therapies based on proliferative index is crucial.
- Awareness of potential dissemination, especially in patients with shunts, is important for clinical management.