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Fragmentation of amidinated peptide ions
Richard L Beardsley1, James P Reilly
1Department of Chemistry, Indiana University, Bloomington, Indiana 47401, USA.
Journal of the American Society for Mass Spectrometry
|February 10, 2004
Abstract:
The collision-induced dissociation characteristics of amidinated and unmodified tryptic peptides are compared using an ion trap mass spectrometer with both electrospray ionization and matrix-assisted laser/desorption ionization (MALDI). Several fragmentation pathways in a number of tryptic peptides of various precursor charge states are found to be enhanced. The additional information conveyed by the observed fragment ions should facilitate protein identifications.