[Dynamics and factors regulating the intensity of free radical processes during experimental supravesical block]

Two phase alterations of induced chemoluminescence were detected in kidney homogenates and blood plasma after unilateral ureteral occlusion in rats. A high correlation was observed between the rates of free radical oxidation in the blocked kidney tissue and blood plasma. Hemodynamic alterations in the kidney, accumulation of activated phagocytes in the interstitial space and elevation of medium-weight molecules were mainly responsible for the regulation of lipid peroxidation rates.