Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
Trachea01:22

Trachea

The trachea, commonly known as the windpipe, is a vital part of the human respiratory system. It serves as a passageway for air to travel between the larynx and the bronchi, allowing oxygen to reach the lungs. Let's explore its anatomical features, dimensions, layers of the tracheal wall, associated muscles, and the functions of its parts.
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of the...
The Bronchial Tree01:23

The Bronchial Tree

The human bronchi and bronchial tree play a crucial role in the respiratory system, facilitating the exchange of oxygen and carbon dioxide. Let's delve into the intricate structure and functions of these respiratory components.
The trachea, commonly known as the windpipe, is a tube that connects the larynx (voice box) to the bronchi. At a point called the carina, it bifurcates into two primary bronchi. The right primary bronchus is wider, shorter, and more vertical than the left primary...
Anatomy of Respiratory System II: Lower Respiratory Tract01:31

Anatomy of Respiratory System II: Lower Respiratory Tract

The lower respiratory tract is anatomically composed of several vital structures, including the larynx, trachea, bronchial tree, alveoli, lungs, and pleurae. Each component has a specific function, and all are intricately connected to ensure efficient respiration.
The Larynx
It is located between the pharynx and the trachea, acts as a passageway for air, and hosts several critical structures, such as the epiglottis, vocal cords, and glottis. The epiglottis acts as a gateway, guiding food to the...
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Pneumothorax-I01:26

Pneumothorax-I

A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterization of the ciliary beating efficiency in primary diffuse chronic rhinosinusitis.

Rhinology·2024
Same author

Filoche et al. Reply.

Physical review letters·2020
Same author

Individual modeling of oxygen capture by the human lungs.

Respiratory physiology & neurobiology·2019
Same author

Diffusion Reaction of Carbon Monoxide in the Human Lung.

Physical review letters·2017
Same author

The Roughton-Forster equation for DL<sub>CO</sub> and DL<sub>NO</sub> re-examined.

Respiratory physiology & neurobiology·2017
Same author

The role of morphology in mathematical models of placental gas exchange.

Journal of applied physiology (Bethesda, Md. : 1985)·2015

Related Experiment Video

Updated: Jun 23, 2026

Bronchoalveolar Lavage (BAL) for Research; Obtaining Adequate Sample Yield
11:47

Bronchoalveolar Lavage (BAL) for Research; Obtaining Adequate Sample Yield

Published on: March 25, 2014

An optimal bronchial tree may be dangerous.

B Mauroy1, M Filoche, E R Weibel

  • 1Centre de Mathématiques et de leurs Applications, Ecole Normale Supérieure de Cachan, 94235 Cachan, France.

Nature
|February 13, 2004
PubMed
Summary

The human bronchial tree

Area of Science:

  • Physiology
  • Biophysics
  • Respiratory System Mechanics

Background:

  • Branched structures like airways are vital for physiological efficiency.
  • Fractal geometry optimizes space-filling and minimizes energy dissipation.
  • The mammalian bronchial tree exemplifies an efficient fractal distribution system.

Purpose of the Study:

  • To investigate the interplay between physical optimization and physiological robustness in human bronchial tree design.
  • To determine if maximum physical efficiency alone is sufficient for physiological function.
  • To understand the implications of optimized bronchial tree geometry for health and disease.

Main Methods:

  • Computational modeling of bronchial tree geometry.
  • Analysis of air flux under varying geometric parameters.

More Related Videos

Isolated Lung Perfusion System in the Rabbit Model
10:18

Isolated Lung Perfusion System in the Rabbit Model

Published on: July 15, 2021

Systematic Bronchoscopy: the Four Landmarks Approach
04:47

Systematic Bronchoscopy: the Four Landmarks Approach

Published on: June 23, 2023

Related Experiment Videos

Last Updated: Jun 23, 2026

Bronchoalveolar Lavage (BAL) for Research; Obtaining Adequate Sample Yield
11:47

Bronchoalveolar Lavage (BAL) for Research; Obtaining Adequate Sample Yield

Published on: March 25, 2014

Isolated Lung Perfusion System in the Rabbit Model
10:18

Isolated Lung Perfusion System in the Rabbit Model

Published on: July 15, 2021

Systematic Bronchoscopy: the Four Landmarks Approach
04:47

Systematic Bronchoscopy: the Four Landmarks Approach

Published on: June 23, 2023

  • Assessment of sensitivity to geometric variations.
  • Main Results:

    • Bronchial tree physical optimization is highly sensitive; small geometric changes drastically alter air flux.
    • Maximum physical efficiency is insufficient as a sole design criterion for physiological robustness.
    • Bronchial tree design necessitates safety factors and airway caliber regulation.

    Conclusions:

    • The human bronchial tree's design balances physical efficiency with physiological robustness.
    • Asthma-related bronchial malfunction may be an unavoidable consequence of this optimized efficiency.
    • Understanding this trade-off is crucial for respiratory health and disease management.