Related Experiment Video
Updated: Jul 15, 2026

Intranasal Administration of CNS Therapeutics to Awake Mice
Published on: April 8, 2013
[The effect on cilia movement of experimental maxillary sinusitis in rabbits with different propose to ostia and
Feng Liu1, Shuimiao Zhou, Zhaoji Li
1Department of Otolaryngology, Changhai Hospital, Second Military Medical University, Shanghai 200433.
Objective:
To investigate the effect on cilia movement of experimental maxillary sinusitis in rabbits with different dispose to ostia and mucosa.
Method:
Forty New Zealand White rabbits which had been induced experimental sinusitis were divided into 3 groups according to mucosa dispose during operation. The another two groups were divided according to different dispose ostia of maxillary sinus. Activated charcoal powder was used to test mucociliary transport (MCT) of maxillary sinus.
Result:
All data had be processed statistically. MCT of rabbits before operation were faster than that after operation and both of them were faster than the sinusitis group(P < 0.01). The difference of MCT in different propose of ostia groups was not significant(P > 0.05).
Conclusion:
It's a effective method to estimate the function of cilia using activated charcoal powder to test MCT of maxillary sinus. The function of regenerate mucosa after operation is lower than normal mucosa. The difference of MCT between ostia enlarged operation and ostia patent surgery is not significant.

