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Published on: August 18, 2023
[Opsoclonus secondary to encephalopolyradiculoneuritis due to Mycoplasma pneumoniae]
C Escorial Moya1, J Rodríguez Baño, M Victoria Borobio
1Servicio de Medicina Interna, Hospital Universitario Virgen Macarena, Sevilla, Spain. cecorial@supercable.es
Abstract:
Opsoclonus is characterized by sudden onset of arrhythmic, multidirectional chaotic eye movements, generally associated with a parainfectious or paraneoplasic condition. Opsoclonus is a rare manifestation with no known link with infection by Mycoplasma pneumoniae. We present a case of a 23 year old male patient who presented fever, myalgia, vomiting, respiratory failure, opsoclonus and symmetric flaccid tetraparesis with important lower limb muscle atrophy. Serology and seroreversion for M. pneumoniae were both positive. This case illustrates the possibility that M. pneumoniae may produce a predominantly neurological disease and the need to include this infection in the differential diagnosis of opsoclonus, or polyradiculoneuritis.
Insights
Mycoplasma pneumoniae infection can cause opsoclonus, a rare chaotic eye movement disorder, and polyradiculoneuritis. This case highlights the need to consider M. pneumoniae in neurological diagnoses.
Area of Science:
- Neurology
- Infectious Diseases
- Ophthalmology
Background:
- Opsoclonus is a rare neurological disorder characterized by chaotic eye movements, typically linked to parainfectious or paraneoplastic conditions.
- Mycoplasma pneumoniae infection is not commonly associated with opsoclonus.
Observation:
- A 23-year-old male presented with fever, myalgia, vomiting, respiratory failure, opsoclonus, and symmetric flaccid tetraparesis with lower limb muscle atrophy.
- Diagnostic workup revealed positive serology and seroreversion for Mycoplasma pneumoniae.
Findings:
- This case demonstrates a potential link between Mycoplasma pneumoniae infection and the development of opsoclonus.
- The patient's presentation suggests M. pneumoniae can cause a predominantly neurological disease.
Implications:
- Mycoplasma pneumoniae should be considered in the differential diagnosis of opsoclonus.
- This finding expands the spectrum of neurological manifestations associated with M. pneumoniae infections, including polyradiculoneuritis.
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