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Updated: Jul 19, 2026

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
Published on: September 9, 2012
[Mutation and unusual expression of clotting system-related genes and hypercoagulability]
1Department of Biochemistry and Molecular Biology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041.
Abstract:
Hypercoagulability is a risk factor for atherosclerosis (As) and plays an important role in the development of As. Hypercoagulability results from mutation and unusual expression of clotting system-related genes, anticlotting system-related genes, fibrinolytic system-related genes and other related genes. Factor V gene, prothrombin gene and tissue factor gene in clotting system, thrombomodulin gene and antithrombin III in anticlotting system, plasminogen activator inhibitor-1 gene in fibrinolytic system, are related with hypercoagulability tightly.
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