Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiple labelled nanoparticles for bio detection.

Frances T Docherty1, Maureen Clark, Graeme McNay

  • 1Department of Pure and Applied Chemistry, University of Strathclyde, Cathedral Street, Glasgow, UK G1 1XL.

Faraday Discussions
|March 3, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Label-Free Visualization of the Antifungal Polyene Drug, Nystatin, in Biological Membranes Using Raman Microscopy.

Analytical chemistry·2026
Same author

Visualization of a Bruton's Tyrosine Kinase Inhibitor Using Fluorescence and Raman Microscopy.

Analytical chemistry·2026
Same author

Development of a surface enhanced Raman scattering lateral flow immunoassay with prolonged reproducibility and stability over time.

The Analyst·2026
Same author

Correction to "Detection of Inflammation in Vivo by Surface-Enhanced Raman Scattering Provides Higher Sensitivity Than Conventional Fluorescence Imaging".

Analytical chemistry·2026
Same author

A Chemical Probe for Prostate-Specific Membrane Antigen for Real-Time Raman Imaging of Prostate Cancer Cells.

ACS sensors·2026
Same author

A SERRS-Based Lateral Flow Assay for Sensitive Detection of Mitochondrial DNA in Endometriosis Screening.

ACS sensors·2026
Same journal

Ambient stability and surface adhesion of 2D polyaramid nanofilms.

Faraday discussions·2026
Same journal

Spiers Memorial Lecture: Spin-mediated promotion of magnetic metal catalysts.

Faraday discussions·2026
Same journal

Helium spin-echo as a surface-sensitive probe of vibrational energy dissipation.

Faraday discussions·2026
Same journal

Near-infrared vibrational second harmonic generation: a new nonlinear interfacial vibrational spectroscopy.

Faraday discussions·2026
Same journal

CO on a Rh/Fe<sub>3</sub>O<sub>4</sub> single-atom catalyst: high-resolution infrared spectroscopy and near-ambient-pressure scanning tunnelling microscopy.

Faraday discussions·2026
Same journal

Evolution of size-selected Pt cluster catalysts on prototypical oxide supports.

Faraday discussions·2026
See all related articles

Researchers developed multiply coded silver nanoparticles for remote detection using surface-enhanced resonance Raman scattering (SERRS). This technique allows for thousands of unique codes, advancing in situ biological probes and bioanalysis.

Area of Science:

  • Nanotechnology
  • Spectroscopy
  • Biotechnology

Background:

  • In situ biological probes require remote nanoparticle detection capabilities.
  • Current methods for nanoparticle detection may have limitations in multiplexing and resolution.

Purpose of the Study:

  • To develop a method for labeling silver nanoparticles to create multiply coded particles.
  • To enable remote detection of these coded nanoparticles using surface-enhanced resonance Raman scattering (SERRS).

Main Methods:

  • Silver nanoparticles were labeled to generate unique spectral codes.
  • Surface-enhanced resonance Raman scattering (SERRS) was employed for particle detection.
  • The potential for multiplexing thousands of codes was investigated.

Related Experiment Videos

Main Results:

  • Successfully created multiply coded silver nanoparticles.
  • Demonstrated the capability of SERRS to detect these coded particles.
  • Showcased the potential for high-capacity multiplexing without spatial resolution requirements.

Conclusions:

  • Multiply coded nanoparticles detected by SERRS offer a promising platform for advanced bioanalysis.
  • This technology facilitates the development of novel in situ biological probes.
  • The system provides a scalable solution for multiplexed detection in biological systems.