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Updated: Aug 25, 2026

Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method
Published on: April 18, 2019
Non-antibiotics--drugs with additional antimicrobial activity
1Department of Antibiotics and Microbiology, National Institute of Public Health (formerly Drug Institute), 30/34 Chełmska Str., 00-725 Warsaw, Poland.
Abstract:
Antimicrobial activity of antibiotics and chemotherapeutics has been investigated for several years. However, a great variety of pharmaceutical preparations, which are applied in the management of non-infectious diseases have shown also some in vitro antimicrobial activity. These drugs are called "non-antibiotics". Detected antimicrobial action of non-antibiotics (and non-chemotherapeutics), emphasises a necessity to neutralise this activity during microbial purity examination in the pharmaceutical industry. It is possible that some of these compounds can enhance the activity of certain antibiotics against bacteria or fungi.
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