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Intrapulmonary teratoma: a case report and review of the literature
D E Morgan1, C Sanders, R B McElvein
1Department of Radiology, School of Medicine, University of Alabama, Birmingham 35233.
Abstract:
Intrapulmonary teratomas are rare; only 30 cases have been reported in the world literature. These tumors are thought to originate from the third pharyngeal pouch. They occur equally in men and women and usually are diagnosed in the second to fourth decade of life. They are more often benign than malignant, although malignant lesions may have a favorable postoperative prognosis and benign lesions may exhibit high morbidity and mortality because of their size and location. These tumors present radiographically as lobulated masses that may contain calcification or peripheral collections of air. They most often occur in the upper lobes. The computed tomographic findings of intrapulmonary teratoma are less well known but have been described in two cases. An additional case is presented with a review of the literature and a tabular summary of the characteristics of this unusual entity.
Insights
Intrapulmonary teratomas, rare lung tumors originating from the third pharyngeal pouch, are usually benign but can cause significant morbidity. This review details their characteristics and diagnostic findings.
Area of Science:
- Thoracic Surgery
- Pulmonology
- Surgical Pathology
Background:
- Intrapulmonary teratomas are exceptionally rare lung neoplasms, with only 30 reported cases globally.
- These tumors are hypothesized to arise from the third pharyngeal pouch, affecting both sexes equally.
- Diagnosis typically occurs between the second and fourth decades of life.
Observation:
- While often benign, intrapulmonary teratomas can present with malignant features, impacting prognosis.
- Radiographic presentation includes lobulated masses, potentially with calcifications or air-fluid levels, predominantly in upper lobes.
- Computed tomography findings are less documented, with limited prior case descriptions.
Findings:
- This report presents an additional case of intrapulmonary teratoma, contributing to the limited literature.
- A comprehensive literature review and tabular summary of tumor characteristics are provided.
- The study highlights the variable clinical behavior, with benign lesions posing risks due to size and location.
Implications:
- Understanding the imaging characteristics, including CT findings, is crucial for accurate diagnosis.
- Despite potential benignancy, the size and location of these tumors necessitate careful management to mitigate morbidity and mortality.
- This case contributes to the collective knowledge of intrapulmonary teratomas, aiding in diagnosis and treatment strategies.