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Updated: Jun 30, 2026

Noninvasive In Vivo Small Animal MRI and MRS: Basic Experimental Procedures
Published on: October 20, 2009
Magnetic resonance imaging using a clinical whole body system: an introduction to a useful technique in small animal
R F Wolf1, K H Lam, E L Mooyaart
1Department of Histology and Cell Biology, Medical Faculty, University of Groningen, The Netherlands.
Abstract:
A clinical whole body magnetic resonance imaging (MRI) system with high resolution coils was used to obtain non-invasive images of the living rat. The results demonstrate the feasibility of the set-up and the advantages of this new imaging technique: detailed information, no extra costs, longitudinal studies without killing animals and simple anaesthesia. It is concluded that in small animal experimentation, this use of high resolution coils in whole body magnetic resonance systems may be particularly helpful in establishing effects of experimental procedures. Whenever non-invasive visualization is required, especially in longitudinal animal studies, e.g. biomaterial research or tumour investigation, this use of MRI will offer challenging possibilities.
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