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Updated: Aug 25, 2026
An Efficient and Rapid HPLC-QQQ-MS Method for the Quantitation of Tropane Alkaloids in Medicinal Plants
Published on: June 12, 2026
[Study on the fingerprints of the alkaloids in Sophora flavescens]
Ren-ling Ma1, Hong-hua Zhou, Xi-shui Yu
1Center for Instrumental Analysis, China Pharmaceutical University, Nanjing 210009, Jiangsu, China. marenling@sohu.com
Objective:
To establish a method for HPLC fingerprint determination of the alkaloids in S. flavescens.
Method:
RP-HPLC, linear gradient elution, LC/MS, etc. were used to determine the fingerprint and identify the main peaks in the HPLC fingerprint.
Result:
A satisfactory method for HPLC fingerprint determination of the alkaloids in S. flavescens. was established, and 5 peaks in the HPLC fingerprint were identified.
Conclusion:
The perfect fingerprint can be obtained and the method can be used for quality control of S. flavescens.
