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Related Experiment Videos

New treatments for tinea capitis.

Yuin-Chew Chan1, Sheila Fallon Friedlander

  • 1National Skin Centre, 1 Mandalay Road, Singapore 308205.

Current Opinion in Infectious Diseases
|March 17, 2004
PubMed
Summary

Newer oral antifungals like terbinafine, itraconazole, and fluconazole offer effective, safe, and shorter treatment options for tinea capitis (scalp ringworm) compared to griseofulvin.

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Area of Science:

  • Dermatology
  • Mycology
  • Infectious Diseases

Background:

  • Tinea capitis is a fungal infection of the scalp, predominantly affecting children.
  • The main pathogens, Trichophyton tonsurans and Microsporum canis, vary geographically.
  • Griseofulvin is the standard U.S. treatment, but newer agents are emerging.

Purpose of the Study:

  • To review the efficacy and safety of newer oral antifungal agents for tinea capitis.
  • To compare these agents with the current standard of care, griseofulvin.
  • To highlight the role of adjuvant topical therapies.

Main Methods:

  • Review of clinical studies and reports on oral antifungal agents for tinea capitis.
  • Evaluation of terbinafine, itraconazole, and fluconazole.
  • Consideration of ketoconazole and selenium sulfide shampoos as adjuvant therapy.

Main Results:

  • Newer oral antifungals (terbinafine, itraconazole, fluconazole) demonstrate effectiveness and safety.
  • These agents offer shorter treatment durations compared to griseofulvin.
  • Limited trials exist for fluconazole, while terbinafine and itraconazole have more documented experience.

Conclusions:

  • Short-term use of terbinafine, itraconazole, and fluconazole is comparable to griseofulvin in efficacy and safety.
  • Epidemiological surveillance of fungal organisms and their susceptibility is crucial for managing tinea capitis.
  • While griseofulvin remains a common choice, newer agents provide viable alternatives.

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