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Novel label-free DNA sensors based on poly(3,4-ethylenedioxythiophene)

K Krishnamoorthy1, Rajesh S Gokhale, Aliasgar Q Contractor

  • 1Chemistry Department, Indian Institute of Technology Bombay, Mumbai 400076, India.

Chemical Communications (Cambridge, England)
|March 27, 2004
PubMed

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Labeling DNA Probes03:31

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DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...