Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Quo vadis elasticity imaging?

E E Konofagou1

  • 1Department of Biomedical Engineering, Columbia University, 1210 Amsterdam Avenue, 351 Engineering Terrace, Mail Code 8, New York, NY 10027, USA. ek2191@columbia.edu

Ultrasonics
|March 30, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Natural aging and Alzheimer's disease pathology increase susceptibility to focused ultrasound-induced blood-brain barrier opening.

Scientific reports·2023
Same author

Long term study of motivational and cognitive effects of low-intensity focused ultrasound neuromodulation in the dorsal striatum of nonhuman primates.

Brain stimulation·2022
Same author

Recombinant BRICHOS chaperone domains delivered to mouse brain parenchyma by focused ultrasound and microbubbles are internalized by hippocampal and cortical neurons.

Molecular and cellular neurosciences·2020
Same author

Power cavitation-guided blood-brain barrier opening with focused ultrasound and microbubbles.

Physics in medicine and biology·2018
Same author

Chirp- and random-based coded ultrasonic excitation for localized blood-brain barrier opening.

Physics in medicine and biology·2015
Same author

Noninvasive, neuron-specific gene therapy can be facilitated by focused ultrasound and recombinant adeno-associated virus.

Gene therapy·2014
Same journal

MUnet: A model-based unrolled reconstruction framework for computational photoacoustic imaging.

Ultrasonics·2026
Same journal

Uncovering the mechanism of ultrasonic cavitation-induced deagglomeration of 7-ADCA agglomerates.

Ultrasonics·2026
Same journal

Identifiability limits in ultrasonic microstructure characterisation using attenuation and velocity features: Canonical analysis and stochastic surrogate modelling.

Ultrasonics·2026
Same journal

A methodology to estimate the ultrasonic p-wave velocity of coarse aggregates in concrete.

Ultrasonics·2026
Same journal

Ultrasonic guided wave damage imaging using the time difference coefficient between direct and scattered waves.

Ultrasonics·2026
Same journal

Axial acoustic radiation force on a sphere embedded in a gel phantom within a focused ultrasound field: simulation and measurement.

Ultrasonics·2026
See all related articles

Elasticity imaging, a complementary technique to ultrasound, visualizes tissue mechanical properties. This advanced method, now clinically applicable in real-time, aids in detecting conditions like tumors and heart disease.

Area of Science:

  • Medical Imaging
  • Biophysics
  • Ultrasound Technology

Background:

  • Elasticity imaging visualizes mechanical properties of tissues, complementing traditional ultrasonic imaging.
  • It leverages differences in tissue mechanical properties and speckle information from ultrasound.
  • Key parameters like strain and elastic modulus can be estimated to identify stiffer tissue masses.

Purpose of the Study:

  • To review the advancements and clinical applicability of elasticity imaging techniques.
  • To highlight the transition of elasticity imaging into routine clinical ultrasound settings.
  • To emphasize its potential contribution to diagnostic ultrasound practices.

Main Methods:

  • Utilizes external or internal mechanical stimuli to assess tissue response.

Related Experiment Videos

  • Employs techniques to estimate parameters such as strain, strain rate, and elastic modulus.
  • Leverages ultrafast algorithms and suitable hardware for real-time elastography.
  • Main Results:

    • Accurate depiction of stiffer tissue masses including tumors, high-intensity focused ultrasound lesions, and atherosclerotic plaques.
    • Real-time elastography (approx. 8 frames/s) is now feasible with hand-held transducers during ultrasound exams.
    • Successful application in imaging myocardium and detecting ischemic regions through deformation monitoring.

    Conclusions:

    • Elasticity imaging is increasingly applicable in clinical settings, particularly for breast and prostate examinations.
    • High frame rates enable cardiac applications, aiding in the detection of myocardial ischemia.
    • This technique promises significant contributions to the future of ultrasound practice.