Related Experiment Video
Updated: Aug 25, 2026

Real-time Analysis of Transcription Factor Binding, Transcription, Translation, and Turnover to Display Global Events During Cellular Activation
Published on: March 7, 2018
Global analysis of bacterial transcription factors to predict cellular target processes
Tobias Doerks1, Miguel A Andrade, Warren Lathe
1EMBL, 69117 Heidelberg, Meyerhofstr 1, Germany. doerks@email.de
Abstract:
Whole-genome sequences are now available for >100 bacterial species, giving unprecedented power to comparative genomics approaches. We have applied genome-context methods to predict target processes that are regulated by transcription factors (TFs). Of 128 orthologous groups of proteins annotated as TFs, to date, 36 are functionally uncharacterized; in our analysis we predict a probable cellular target process or biochemical pathway for half of these functionally uncharacterized TFs.
More Related Videos
Related Concept Videos
General Transcription Factors
Transcription Factors
Transcription Factors
Bacterial RNA Polymerase
In most genes, the transcription site is a single base present upstream of the coding sequence. Though RNAP is a catalytically efficient enzyme, it does not recognize...
Prokaryotic Transcriptional Activators and Repressors
Transcription of prokaryotic...
Prokaryotic Transcriptional Activators and Repressors
Transcription of prokaryotic...

