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Updated: Aug 25, 2026

Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics
Published on: May 11, 2016
Branchiogenic squamous cell carcinoma: a case report
1Department of Otolaryngology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Abstract:
Branchiogenic carcinoma is extremely rare. A 41-year-old man presented with a well-defined, fluctuant, painless mass on his right neck and received complete tumour excision. The pathological diagnosis was branchial cleft squamous cell carcinoma, which was characterized microscopically by a branchial cleft cyst with a tumour and a non-tumour transitional zone. In the past, several hundred cases were reported erroneously because of the rather complicated diagnostic criteria. The modified criteria of Khafif introduced in 1989 are more practical, and all were met in this case.
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