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Updated: Aug 25, 2026

Murine Full-thickness Skin Transplantation
Published on: January 2, 2017
The historical link between solid-organ transplantation, immunosuppression, and skin cancer
1Department of Dermatology, Mayo Clinic, Jacksonville, Florida 32224, USA. randle.henry@mayo.edu
Background:
Skin cancers are more common in organ transplant recipients than in the general population.
Objective:
The objective of this study was establish the historical link between organ transplantation, immunosuppression, and the development of skin cancer.
Methods:
The pertinent literature in cutaneous oncology and transplantation is reviewed.
Results:
There is a historical link between organ transplants, immunosuppression, and the subsequent development of skin cancers.
Conclusions:
Organ transplant recipients have more skin cancer than those in the general population and this is temporally related to their degree of immunosuppression.
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