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Updated: Aug 25, 2026

Spatiotemporal Mapping of Motility in Ex Vivo Preparations of the Intestines
Published on: January 27, 2016
[Probable mechanisms of the regulation in the jejunum motility]
A E Lychkova1, V I Savchuk, V M Smirnov
1Central Scientific Research Institute of Gastroenterology, Russian State Medical University, Moscow.
Abstract:
It is a well-known fact that serotonin has a stimulative action on the motor-secretory activity of the gastrointestinal tract. Activation of 5HT3,4-receptors regulates neuronal responses of this action; it is possible to regulate efferent reactions by activating 5HT1,2-receptors (1, 2, 3). Carcinoid cells containing 5HT have 5HT3 and 5HT4 receptors on their superficial membranes. The object of this research was to determine the possible participation of serotonergic structures in the regulation of the jejunum motility.
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