Related Experiment Video
Updated: Jan 4, 2026

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
Published on: February 6, 2020
Incorporation of a flexible, pyridine-functionalized Diaza-crown ether into discrete supramolecules via
Ki-Whan Chi1, Chris Addicott, Peter J Stang
1Department of Chemistry, University of Utah, 315 S. 1400 E. Salt Lake City, Utah 84112, USA.
Abstract:
A flexible, pyridine-functionalized diaza-crown ether was self-assembled into discrete supramolecules of differing stoichiometries upon combination with various organoplatinum molecules. They are characterized by electrospray ionization mass spectrometry and (31)P[(1)H] and (1)H NMR. In one case, (1)H-(1)H NOE enhancements of a [1 + 1] assembled structure demonstrate the puckered shape of the macrocyclic ring. Despite its inherent flexibility, the dipyridyl-substituted 18-membered diaza-crown ligand prefers to self-assemble into closed systems when reacted with platinum-containing acceptors.
Related Concept Videos
Crown Ethers
[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction
Diels–Alder Reaction Forming Cyclic Products: Stereochemistry
Cycloaddition Reactions: Overview
Diels–Alder Reaction Forming Bridged Bicyclic Products: Stereochemistry
[3,3] Sigmatropic Rearrangement of 1,5-Dienes: Cope Rearrangement

