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Processed human pericardium barrier for gold weight implantation
Jill A Foster1, Julian D Perry, Kenneth V Cahill
1Grant Eye and Ear Hospital, the Ohio State University, Columbus, Ohio 44195, USA.
Ophthalmic Plastic and Reconstructive Surgery
|April 15, 2004
Summary
Processed human pericardium is a safe and effective barrier material for gold weight implantation in eyelids. This study found no major complications, indicating good short-term tolerance for this ophthalmic surgical application.
Area of Science:
- Ophthalmic surgery
- Biomaterials science
- Tissue engineering
Background:
- Gold weight implantation is a common treatment for eyelid retraction.
- Thinning of overlying tissues or implant extrusion can complicate gold weight procedures.
- Alternative barrier materials are sought to improve outcomes and patient safety.
Purpose of the Study:
- To evaluate the safety and efficacy of processed human pericardium as a barrier material during gold weight implantation.
- To assess complication rates and tissue integration of human pericardium in eyelid surgery.
Main Methods:
- A retrospective case series of 23 patients undergoing gold weight implantation with human pericardium barrier between 2000 and 2002.
- Surgical indications, implant details, follow-up intervals, and complications were reviewed from patient charts.
Main Results:
- Twenty-three eyelids received gold weight implantation using human pericardium.
- Indications included prior extrusion, thin tissues, radiotherapy, and long-term therapy needs.
- All 23 eyelids achieved acceptable tissue coverage with no infections or extrusions; one case of prolonged edema resolved spontaneously.
Conclusions:
- Processed human pericardium demonstrates good short-term tolerance and efficacy as a barrier material for gold weight implantation.
- This biomaterial appears to be a safe option for protecting overlying eyelid tissues in various clinical scenarios.