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Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-(phosphinetriyl)tripiperidine]}palladium Under Mild Reaction Conditions
Published on: March 21, 2014
Palladium catalyzed cross-coupling reactions for phosphorus-carbon bond formation
1Dept. of Chemistry and Biochemistry, University of Guelph, Guelph, Ontario, Canada N1G 2W1.
Abstract:
Underappreciated in the realm of palladium catalyzed cross-coupling chemistry is the formation of phosphorous-carbon bonds. This tutorial review summarises a collection of important contributions in the area, providing a flavour of the many types of phosphorus species that are participants in palladium catalyzed phosphorus-carbon bond formation. Recent developments include the usage of the cross-coupling reaction for preparation of phosphine ligands and the involvement of low molecular weight phosphinic acid derivatives for the synthesis of unsaturated phosphinic and phosphonic acid derivatives. Mechanistic cycles are offered in some instances. Stereochemical issues are addressed where applicable. The literature is covered to mid 2003.
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