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[Reduced intensity stem cell transplantation for metastatic renal cell carcinoma]
So Omori1, Tomoaki Fujioka, Yoko Ono
1Department of Urology, Iwate Medical University.
Purpose:
We reviewed reduced intensity stem cell transplantation (RIST) in metastatic renal cell cancer (RCC).
Patients And Methods:
Two cases of lung metastasis of immunotherapy invalidity. Six days of fludarabine 30 mg/m2 and 2 days of busulfan 4 mg/kg were given as conditioning for mini-SCT. CyA and short-term MTX were used as immunosuppressive agents.
Results:
Size reduction of tumor was observed with dose reduction of CyA. Following steroid therapy for the treatment of GVHD, the tumor progressed. No serious complications except for GVHD.
Conclusion:
These results suggested that RIST might be considered as salvage therapy in patients metastatic RCC.
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