Related Experiment Videos
Bacteriological profile in chronic suppurative otitis media in Eastern Nepal
Satyender Sharma1, Harmeet Singh Rehan, Arun Goyal
1Department of Otorhinolaryngology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal, India.
Tropical Doctor
|May 1, 2004
Summary
Ciprofloxacin is a preferred treatment for chronic suppurative otitis media (CSOM) due to its effectiveness and safety profile. This study highlights its advantages over aminoglycosides for managing CSOM infections.
Area of Science:
- Otolaryngology
- Infectious Diseases
- Microbiology
Background:
- Chronic suppurative otitis media (CSOM) is a persistent ear infection.
- Identifying causative pathogens and their antibiotic sensitivities is crucial for effective treatment.
Purpose of the Study:
- To determine the microbial profile of CSOM.
- To evaluate the in vitro antibiotic susceptibility patterns of isolated organisms.
Main Methods:
- Aural swabs were collected from 250 patients with chronic suppurative otitis media.
- Culture and sensitivity testing were performed on isolated organisms.
- Prevalence of Pseudomonas aeruginosa and Staphylococcus aureus was analyzed.
Main Results:
- Pseudomonas aeruginosa (36.4%) and Staphylococcus aureus (30.2%) were the most common isolates.
- Gram-negative bacteria were sensitive to ciprofloxacin, amikacin, ofloxacin, and gentamycin.
- Gram-positive bacteria showed sensitivity to cloxacillin, ofloxacin, erythromycin, ciprofloxacin, gentamicin, and tetracycline.
- Amoxycillin resistance was observed in most isolates.
Conclusions:
- Ciprofloxacin is recommended for CSOM treatment due to efficacy, lower cost, and reduced ototoxicity compared to aminoglycosides.
- Topical and oral ciprofloxacin preparations offer a valuable therapeutic option for CSOM.