Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hypoglycemia in diabetes: common, often unrecognized.

Ilan Gabriely1, Harry Shamoon

  • 1Diabetes Research Center, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

Cleveland Clinic Journal of Medicine
|May 1, 2004
PubMed
Summary

Hypoglycemic episodes in patients with diabetes can go unnoticed, leading to a dangerous loss of awareness. Intensive diabetes control, while beneficial, heightens this hypoglycemia risk, complicating diabetes management.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of Intranasal Naloxone on Hypoglycemia-associated Autonomic Failure in Susceptible Individuals.

The Journal of clinical endocrinology and metabolism·2024
Same author

Plasma Epinephrine Contributes to the Development of Experimental Hypoglycemia-Associated Autonomic Failure.

The Journal of clinical endocrinology and metabolism·2020
Same author

Acute milk-alkali syndrome

Endocrinology, diabetes & metabolism case reports·2018
Same author

Primary Hyperparathyroidism in Pregnancy: Successful Parathyroidectomy during First Trimester.

Case reports in endocrinology·2018
Same author

Potential approaches to prevent hypoglycemia-associated autonomic failure.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research·2017
Same author

Opioid Receptor Activation Impairs Hypoglycemic Counterregulation in Humans.

Diabetes·2017

Area of Science:

  • Endocrinology
  • Metabolic Disorders
  • Clinical Diabetes Research

Background:

  • Hypoglycemic episodes are common in diabetes management.
  • Prolonged or frequent hypoglycemia can lead to impaired hypoglycemia awareness.
  • This unawareness increases the risk of severe hypoglycemic events and complications.

Purpose of the Study:

  • To highlight the risks associated with unrecognized hypoglycemia in diabetic patients.
  • To underscore the complex balance between intensive glycemic control and hypoglycemia risk.
  • To emphasize the challenges in managing diabetes, particularly concerning hypoglycemia unawareness.

Main Methods:

  • This abstract is based on a review of existing literature and clinical observations regarding hypoglycemia in diabetes.
  • Analysis of the impact of intensive diabetes control strategies on hypoglycemia incidence.
  • Evaluation of the physiological mechanisms underlying impaired hypoglycemia awareness.

Main Results:

  • Unrecognized hypoglycemic episodes are a significant concern in diabetes care.
  • Intensive diabetes control regimens are associated with an increased frequency of hypoglycemia.
  • Patients with diabetes may progressively lose their ability to sense low blood glucose levels.

Conclusions:

  • Effective diabetes management requires careful consideration of hypoglycemia risks.
  • Strategies must be developed to mitigate hypoglycemia and preserve awareness in patients with diabetes.
  • The complexity of diabetes necessitates a nuanced approach to treatment balancing glycemic targets and safety.

Related Experiment Videos