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Corneal thickness in congenital glaucoma
Marta Junqueira Henriques1, Roberto Murad Vessani, Frederico Augusto Costa Reis
1Department of Ophthalmology, University of São Paulo and Santa Casa de Misericórdia de São Paulo, Sao Paulo, Brazil.
Journal of Glaucoma
|May 1, 2004
Summary
Children with congenital glaucoma have thinner central corneal thickness. This finding is important for accurate intraocular pressure (IOP) measurement in pediatric glaucoma patients.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Glaucoma Research
Background:
- Congenital glaucoma is a rare condition affecting infants.
- Accurate intraocular pressure (IOP) measurement is crucial for managing glaucoma.
- Central corneal thickness (CCT) can influence IOP readings.
Purpose of the Study:
- To compare central corneal thickness (CCT) in children with congenital glaucoma versus healthy controls.
- To investigate the correlation between CCT, corneal diameter, and axial length in these groups.
Main Methods:
- Ophthalmologic examination, CCT, axial length, and corneal diameter measurements were performed on 55 children (30 with congenital glaucoma, 25 controls) under general anesthesia.
- Patients had IOP < 21 mm Hg and no corneal edema.
Main Results:
- Children with congenital glaucoma had significantly thinner CCT compared to controls (P = 0.01).
- Corneal diameter and axial length were also significantly different between the groups (P < 0.0001).
- Significant correlations were found between CCT and corneal diameter (r2 = 0.32) and between CCT and axial length (r2 = 0.18).
Conclusions:
- Central corneal thickness is significantly reduced in children with congenital glaucoma.
- Thinner CCT may confound IOP measurements in pediatric glaucoma patients.
- Pachymetry is recommended during the ophthalmic examination of children with congenital glaucoma.