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Metastatic mesothelioma presenting with proptosis
Andrew Gibson1, Fawaz Musa, Andrew Pearson
1Prince Charles Eye Unit, King Edward VII Hospital, Windsor, United Kingdom. agibson@tinyonline.co.uk
Purpose:
To describe the clinical presentation and histologic findings in a patient with metastatic mesothelioma presenting to the ophthalmologist with nonaxial proptosis.
Design:
Case report.
Methods:
A 55-year-old man presented with a short history of progressive ocular discomfort and vertical diplopia. Clinical examination identified nonaxial proptosis. Subsequent computed tomography showed a large extraconal mass consistent with a malignant process. Three months earlier the patient had been diagnosed with pleural mesothelioma. Unfortunately, he died 3 months after his ophthalmic presentation. Postmortem examination confirmed metastatic mesothelioma in the orbital roof that was histologically identical to the primary pleural malignancy.
Conclusion:
Pleural mesothelioma can metastasize to the orbit, causing proptosis.