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Markers of altered metabolism in osteoarthritis

L Stefan Lohmander1

  • 1Department of Orthopaedics, Lund University Hospital, Lund, Sweden. stefan.lohmander@ort.lu.se

The Journal of Rheumatology. Supplement
|May 11, 2004
PubMed
Abstract

No abstract available in PubMed .

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Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...