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Protection of Alcohols02:31

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This lesson delves into the concept of protection and deprotection of a functional group fundamental to synthetic organic chemistry. These phenomena are explained in the context of aliphatic and aromatic alcohols.
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Grignard reagents are one of the most commonly used reagents used to synthesize alcohols from carbonyl compounds. Grignard reagents are organomagnesium halides with a highly polar carbon–magnesium bond. Due to the partial ionic nature of the C–Mg bond, the carbon functions as a strong nucleophile and attacks electrophiles like carbonyl carbon.
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Esters to Alcohols: Grignard Reaction01:08

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The reaction of an ester with a Grignard reagent, followed by hydrolysis of the magnesium alkoxide salt in aqueous acid, yields a tertiary alcohol. In the case of formate esters, secondary alcohols are formed.
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Author Spotlight: Exploring the Fermentation Microbiome Through Next-Generation Sequencing
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GRAPPA 2020 Update From the Education Committee.

Philip J Mease1, Amit Garg2, Philip S Helliwell

  • 1P.J. Mease, MD, Rheumatology Research, Swedish Medical Center/Providence St. Joseph Health and University of Washington School of Medicine, Seattle, Washington, USA; pmease@philipmease.com.

The Journal of Rheumatology. Supplement
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Summary
This summary is machine-generated.

The COVID-19 pandemic prompted a review of virtual symposia. Future directions and diverse topics for online meetings were explored to adapt to travel restrictions.

Keywords:
GRAPPAeducationpsoriasispsoriatic arthritis

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Area of Science:

  • Medical Education
  • Public Health
  • Infectious Diseases

Background:

  • COVID-19 (coronavirus disease 2019; caused by SARS-CoV-2) pandemic led to global travel restrictions.
  • Virtual meetings and symposia emerged as crucial communication tools in 2021.
  • The education committee recognized the need to adapt scientific exchange formats.

Purpose of the Study:

  • To review and propose future directions for virtual symposia.
  • To identify diverse topics suitable for online scientific exchange.
  • To ensure continued education and collaboration despite pandemic-related limitations.

Main Methods:

  • Review of current trends in virtual scientific meetings.
  • Brainstorming and discussion of potential topics for virtual symposia.
  • Consideration of best practices for online engagement and knowledge sharing.

Main Results:

  • Identification of key areas and topics amenable to virtual presentation.
  • Development of strategies for effective virtual symposium organization.
  • Recognition of the sustained importance of virtual formats in scientific discourse.

Conclusions:

  • Virtual symposia are essential for maintaining scientific progress during and after the pandemic.
  • A diverse range of topics can be successfully delivered through virtual platforms.
  • Proactive planning for virtual events is crucial for the education committee.