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Updated: Aug 12, 2026

Microfluidic Mixers for Studying Protein Folding
Published on: April 10, 2012
A fast passive and planar liquid sample micromixer
Jessica Melin1, Guillem Gimenéz, Niclas Roxhed
1Microsystem Technology, Department of Signals, Sensors and Systems, Royal Institute of Technology, SE 100 44, Stockholm, Sweden.
Abstract:
A novel microdevice for passively mixing liquid samples based on surface tension and a geometrical mixing chamber is presented. Due to the laminar flow regime on the microscale, mixing becomes difficult if not impossible. We present a micromixer where a constantly changing time dependent flow pattern inside a two sample liquid plug is created as the plug simply passes through the planar mixer chamber. The device requires no actuation during mixing and is fabricated using a single etch process. The effective mixing of two coloured liquid samples is demonstrated.

