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Size-selective extraction of peptides from urine for mass spectrometric analysis

Glen L Hortin1, Bonnie Meilinger, Steven K Drake

  • 1Department of Laboratory Medicine, Warren Magnuson Clinical Center, NIH, Bethesda, MD, USA. ghortin@mail.cc.nih.gov

Clinical Chemistry
|May 27, 2004
PubMed
Abstract

No abstract available in PubMed .

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Peptide Identification Using Tandem Mass Spectrometry

Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...